The April 1 issue (-giggle-) of PLOS ONE published an article on the alternative medicine modality of electro-acupuncture (EA) by a group of investigators from Shanghai, China (DOI: 10.1371/journal.pone.0122087). The basic premises of the study are sound:
In the wake of my recent critique of acupuncture being touted as a remedy for allergic rhinitis, I was pointed (via a Twitter comment) towards a 2013 review in Evidence Based Complementary and Alternative Medicine, which purported to propose a mechanism for the much-claimed anti-inflammatory effects of acupuncture. There are several putative mechanisms, discussing all of which will make this post gargantuan. Therefore, I shall focus on the explanation involving the hypothalamus-pituitary-adrenal (HPA) axis.